Peripheral Neuropathy / Arthralgia

Peripheral Neuropathy
Use of chemotherapeutic agents such as paclitaxel (Taxol) and docetaxel (Taxotere) may cause:

  • Numbness
  • Tingling
  • “Pins and needles” pain affecting the fingers, toes and feet

Some patients may experience late onset. Usual treatments for neuropathic pain may not be effective.
Usually peripheral neuropathy resolves over time – months to years.

Refer intractable cases back to LRCP Pain Clinic through New Patient Referral.


  • Arthralgia and myalgia are common complaints in patients receiving therapy with aromataseinhibitors (letrozole, anastrazole, and exemestane)
  • Described as joint stiffness, pain in the wrists, hips, knees and ankles improving over the day
  • Usually decreases over the first 1-2 years of treatment


  • Maintain an exercise program
  • Physiotherapy
  • Massage therapy
  • Anti-inflammatories

Some patients may require a change in therapy to another agent – Please refer back to the oncologist